H67Q (p.His67Gln) variant of SOST (Sclerostin)
H67Q (p.His67Gln) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
H67Q (p.His67Gln) variant details
- p.His67Gln
- TOPMed rs1330217415
- gnomAD rs1330217415
- Missense
- Variant Prioritization Score for Impact Estimate 0.162
- REVEL 0.06
- CADD 17.50
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available