H15R (p.His15Arg) variant of SOST (Sclerostin)
H15R (p.His15Arg) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
H15R (p.His15Arg) variant details
- p.His15Arg
- 1000Genomes rs528251296
- ExAC rs528251296
- gnomAD rs528251296
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.15
- CADD 13.50
- PolyPhen-2 0.00
- SIFT 0.64
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available