H15P (p.His15Pro) variant of SOST (Sclerostin)
H15P (p.His15Pro) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
H15P (p.His15Pro) variant details
- p.His15Pro
- 1000Genomes rs528251296
- ExAC rs528251296
- gnomAD rs528251296
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- REVEL 0.48
- CADD 16.80
- PolyPhen-2 0.22
- SIFT 0.25
- Most common in the 1KG:IBS population (allele frequency 0.0048)
- Structural context available