G92V (p.Gly92Val) variant of SOST (Sclerostin)
G92V (p.Gly92Val) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data, published literature, and structural context.
G92V (p.Gly92Val) variant details
- p.Gly92Val
- gnomAD 17-43755709-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.835
- REVEL 0.87
- MetaLR 0.76
- MetaSVM 0.66
- CADD 29.10
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available