G92R (p.Gly92Arg) variant of SOST (Sclerostin)
G92R (p.Gly92Arg) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
G92R (p.Gly92Arg) variant details
- p.Gly92Arg
- gnomAD 17-43755710-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.715
- REVEL 0.76
- MetaLR 0.56
- MetaSVM 0.08
- CADD 25.60
- PolyPhen-2 0.21
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available