F85S (p.Phe85Ser) variant of SOST (Sclerostin)
F85S (p.Phe85Ser) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
F85S (p.Phe85Ser) variant details
- p.Phe85Ser
- gnomAD 17-43755730-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.12
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available