E77G (p.Glu77Gly) variant of SOST (Sclerostin)
E77G (p.Glu77Gly) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
E77G (p.Glu77Gly) variant details
- p.Glu77Gly
- gnomAD 17-43755754-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.28
- CADD 23.70
- PolyPhen-2 0.04
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available