E77D (p.Glu77Asp) variant of SOST (Sclerostin)
E77D (p.Glu77Asp) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
E77D (p.Glu77Asp) variant details
- p.Glu77Asp
- gnomAD 17-43755753-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.21
- CADD 18.30
- PolyPhen-2 0.00
- SIFT 0.31
- Population evidence available
- Structural context available
- Literature evidence available