E77* (p.Glu77Ter) variant of SOST (Sclerostin)
E77* (p.Glu77Ter) in SOST (Sclerostin) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data, published literature, and structural context.
E77* (p.Glu77Ter) variant details
- p.Glu77Ter
- gnomAD 17-43755755-C-A
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.751
- CADD 37.00
- Most common in the Non-Finnish European population (allele frequency 7.2e-06)
- Structural context available
- Literature evidence available