E60K (p.Glu60Lys) variant of SOST (Sclerostin)
E60K (p.Glu60Lys) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
E60K (p.Glu60Lys) variant details
- p.Glu60Lys
- gnomAD rs1286080574
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.12
- CADD 18.90
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 5.6e-05)
- Structural context available