D91Y (p.Asp91Tyr) variant of SOST (Sclerostin)
D91Y (p.Asp91Tyr) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
D91Y (p.Asp91Tyr) variant details
- p.Asp91Tyr
- gnomAD 17-43755713-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.783
- REVEL 0.76
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available