D91E (p.Asp91Glu) variant of SOST (Sclerostin)
D91E (p.Asp91Glu) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
D91E (p.Asp91Glu) variant details
- p.Asp91Glu
- gnomAD 17-43755711-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.23
- MetaLR 0.29
- MetaSVM -0.99
- CADD 17.40
- PolyPhen-2 0.01
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available