D74E (p.Asp74Glu) variant of SOST (Sclerostin)
D74E (p.Asp74Glu) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
D74E (p.Asp74Glu) variant details
- p.Asp74Glu
- gnomAD 17-43755762-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.04
- CADD 17.10
- PolyPhen-2 0.00
- SIFT 0.45
- Population evidence available
- Structural context available
- Literature evidence available