A33V (p.Ala33Val) variant of SOST (Sclerostin)
A33V (p.Ala33Val) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
A33V (p.Ala33Val) variant details
- p.Ala33Val
- ExAC rs748258858
- gnomAD rs748258858
- Missense
- Variant Prioritization Score for Impact Estimate 0.76
- REVEL 0.74
- CADD 27.40
- PolyPhen-2 0.76
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available