W31G (p.Trp31Gly) variant of SORL1 (Sortilin-related receptor)
W31G (p.Trp31Gly) in SORL1 (Sortilin-related receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
W31G (p.Trp31Gly) variant details
- p.Trp31Gly
- gnomAD 11-121452422-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.29
- MetaLR 0.43
- MetaSVM -0.62
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 0.78
- Population evidence available
- Structural context available
- Literature evidence available