L22L (p.Leu22Leu) variant of SORL1 (Sortilin-related receptor)
L22L (p.Leu22Leu) in SORL1 (Sortilin-related receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
L22L (p.Leu22Leu) variant details
- p.Leu22Leu
- rs866322118
- gnomAD 11-121452395-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.493
- CADD 15.50
- Population evidence available
- Structural context available
- Literature evidence available