S35T (p.Ser35Thr) variant of SOD1 (Superoxide dismutase [Cu-Zn])
S35T (p.Ser35Thr) in SOD1 (Superoxide dismutase [Cu-Zn]) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
S35T (p.Ser35Thr) variant details
- p.Ser35Thr
- gnomAD 21-31663821-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.22
- MetaLR 0.89
- MetaSVM 0.82
- CADD 5.25
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available
- Literature evidence available