K10N (p.Lys10Asn) variant of SOD1 (Superoxide dismutase [Cu-Zn])
K10N (p.Lys10Asn) in SOD1 (Superoxide dismutase [Cu-Zn]) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
K10N (p.Lys10Asn) variant details
- p.Lys10Asn
- gnomAD 21-31659799-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.72
- MetaLR 0.97
- MetaSVM 1.04
- CADD 23.40
- PolyPhen-2 0.68
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available
- Literature evidence available