V45D (p.Val45Asp) variant of SOCS1 (O15524)
V45D (p.Val45Asp) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
V45D (p.Val45Asp) variant details
- p.Val45Asp
- gnomAD 16-11255345-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0867
- REVEL 0.02
- MetaLR 0.03
- MetaSVM -1.03
- CADD 7.94
- PolyPhen-2 0.01
- SIFT 0.59
- Population evidence available
- Structural context available
- Literature evidence available