V2L (p.Val2Leu) variant of SOCS1 (O15524)
V2L (p.Val2Leu) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
V2L (p.Val2Leu) variant details
- p.Val2Leu
- cosmic curated COSV59661
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.11
- CADD 23.80
- PolyPhen-2 0.29
- SIFT 0.00
- Population evidence available
- Structural context available