V2A (p.Val2Ala) variant of SOCS1 (O15524)
V2A (p.Val2Ala) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
V2A (p.Val2Ala) variant details
- p.Val2Ala
- cosmic curated COSV10524
- 1000Genomes rs2141125567
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.12
- CADD 24.00
- PolyPhen-2 0.21
- SIFT 0.00
- Most common in the 1KG:MSL population (allele frequency 0.0063)
- Structural context available