V13L (p.Val13Leu) variant of SOCS1 (O15524)
V13L (p.Val13Leu) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
V13L (p.Val13Leu) variant details
- p.Val13Leu
- cosmic curated COSV10524
- ExAC rs200748141
- TOPMed rs200748141
- gnomAD rs200748141
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.07
- CADD 19.60
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available