T15I (p.Thr15Ile) variant of SOCS1 (O15524)
T15I (p.Thr15Ile) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
T15I (p.Thr15Ile) variant details
- p.Thr15Ile
- cosmic curated COSV10739
- 1000Genomes rs753381473
- ExAC rs753381473
- TOPMed rs753381473
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.09
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the 1KG:CDX population (allele frequency 0.0057)
- Structural context available