S30F (p.Ser30Phe) variant of SOCS1 (O15524)
S30F (p.Ser30Phe) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
S30F (p.Ser30Phe) variant details
- p.Ser30Phe
- Ensembl rs2141125386
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.15
- CADD 24.60
- PolyPhen-2 0.83
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 3.1e-06)
- Structural context available