S29F (p.Ser29Phe) variant of SOCS1 (O15524)
S29F (p.Ser29Phe) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S29F (p.Ser29Phe) variant details
- p.Ser29Phe
- cosmic curated COSV10524
- Ensembl rs1597691601
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.06
- CADD 28.90
- PolyPhen-2 0.83
- SIFT 0.04
- Most common in the HGDP:OROQEN population (allele frequency 0.062)
- Structural context available