S28P (p.Ser28Pro) variant of SOCS1 (O15524)
S28P (p.Ser28Pro) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S28P (p.Ser28Pro) variant details
- p.Ser28Pro
- 1000Genomes rs2141125399
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.07
- CADD 21.60
- PolyPhen-2 0.10
- SIFT 0.21
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available