S28F (p.Ser28Phe) variant of SOCS1 (O15524)
S28F (p.Ser28Phe) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
S28F (p.Ser28Phe) variant details
- p.Ser28Phe
- cosmic curated COSV59660
- TOPMed rs1359050527
- gnomAD rs1359050527
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.05
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available