S26P (p.Ser26Pro) variant of SOCS1 (O15524)
S26P (p.Ser26Pro) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S26P (p.Ser26Pro) variant details
- p.Ser26Pro
- Ensembl rs2069586680
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.03
- CADD 22.90
- PolyPhen-2 0.44
- SIFT 0.19
- Most common in the South Asian population (allele frequency 5.1e-05)
- Structural context available