S26F (p.Ser26Phe) variant of SOCS1 (O15524)
S26F (p.Ser26Phe) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S26F (p.Ser26Phe) variant details
- p.Ser26Phe
- TOPMed rs1419275878
- gnomAD rs1419275878
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.03
- CADD 24.70
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the South Asian population (allele frequency 2.5e-05)
- Structural context available