S14C (p.Ser14Cys) variant of SOCS1 (O15524)
S14C (p.Ser14Cys) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
S14C (p.Ser14Cys) variant details
- p.Ser14Cys
- cosmic curated COSV10524
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.04
- CADD 24.20
- PolyPhen-2 0.18
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available