R40W (p.Arg40Trp) variant of SOCS1 (O15524)
R40W (p.Arg40Trp) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R40W (p.Arg40Trp) variant details
- p.Arg40Trp
- TOPMed rs1287870158
- gnomAD rs1287870158
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.08
- CADD 26.60
- PolyPhen-2 0.82
- SIFT 0.04
- Population evidence available
- Structural context available