R38L (p.Arg38Leu) variant of SOCS1 (O15524)
R38L (p.Arg38Leu) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
R38L (p.Arg38Leu) variant details
- p.Arg38Leu
- gnomAD rs1248355267
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.08
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available