R38C (p.Arg38Cys) variant of SOCS1 (O15524)
R38C (p.Arg38Cys) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
R38C (p.Arg38Cys) variant details
- p.Arg38Cys
- cosmic curated COSV59660
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.05
- CADD 25.20
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 3e-05)
- Structural context available