Q6P (p.Gln6Pro) variant of SOCS1 (O15524)
Q6P (p.Gln6Pro) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
Q6P (p.Gln6Pro) variant details
- p.Gln6Pro
- 1000Genomes rs2141125550
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.10
- CADD 23.00
- PolyPhen-2 0.28
- SIFT 0.20
- Most common in the 1KG:IBS population (allele frequency 0.0048)
- Structural context available