P46T (p.Pro46Thr) variant of SOCS1 (O15524)
P46T (p.Pro46Thr) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
P46T (p.Pro46Thr) variant details
- p.Pro46Thr
- gnomAD 16-11255343-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.15
- REVEL 0.05
- MetaLR 0.04
- MetaSVM -0.99
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available