P46R (p.Pro46Arg) variant of SOCS1 (O15524)
P46R (p.Pro46Arg) in SOCS1 (O15524) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
P46R (p.Pro46Arg) variant details
- p.Pro46Arg
- gnomAD 16-11255341-CG-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.381
- CADD 25.60
- Population evidence available
- Structural context available
- Literature evidence available