P46Q (p.Pro46Gln) variant of SOCS1 (O15524)
P46Q (p.Pro46Gln) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
P46Q (p.Pro46Gln) variant details
- p.Pro46Gln
- gnomAD 16-11255342-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.04
- MetaLR 0.03
- MetaSVM -0.92
- CADD 20.70
- PolyPhen-2 0.08
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available