P43S (p.Pro43Ser) variant of SOCS1 (O15524)
P43S (p.Pro43Ser) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P43S (p.Pro43Ser) variant details
- p.Pro43Ser
- cosmic curated COSV59659
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.01
- CADD 17.30
- PolyPhen-2 0.01
- SIFT 0.67
- Most common in the South Asian population (allele frequency 2.1e-05)
- Structural context available