P39R (p.Pro39Arg) variant of SOCS1 (O15524)
P39R (p.Pro39Arg) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P39R (p.Pro39Arg) variant details
- p.Pro39Arg
- ExAC rs776843433
- TOPMed rs776843433
- gnomAD rs776843433
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.02
- CADD 15.90
- PolyPhen-2 0.02
- SIFT 0.22
- Most common in the South Asian population (allele frequency 0.001)
- Structural context available