P39Q (p.Pro39Gln) variant of SOCS1 (O15524)
P39Q (p.Pro39Gln) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P39Q (p.Pro39Gln) variant details
- p.Pro39Gln
- cosmic curated COSV59661
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.03
- CADD 16.80
- PolyPhen-2 0.31
- SIFT 0.12
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available