P23S (p.Pro23Ser) variant of SOCS1 (O15524)
P23S (p.Pro23Ser) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
P23S (p.Pro23Ser) variant details
- p.Pro23Ser
- gnomAD rs1486450287
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.02
- CADD 21.60
- PolyPhen-2 0.01
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available