P23R (p.Pro23Arg) variant of SOCS1 (O15524)
P23R (p.Pro23Arg) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
P23R (p.Pro23Arg) variant details
- p.Pro23Arg
- TOPMed rs2069586736
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.05
- CADD 23.00
- PolyPhen-2 0.05
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available