P19T (p.Pro19Thr) variant of SOCS1 (O15524)
P19T (p.Pro19Thr) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P19T (p.Pro19Thr) variant details
- p.Pro19Thr
- 1000Genomes rs1028027657
- TOPMed rs1028027657
- gnomAD rs1028027657
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.05
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available