P19S (p.Pro19Ser) variant of SOCS1 (O15524)
P19S (p.Pro19Ser) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P19S (p.Pro19Ser) variant details
- p.Pro19Ser
- cosmic curated COSV10524
- 1000Genomes rs1028027657
- TOPMed rs1028027657
- gnomAD rs1028027657
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.04
- CADD 18.50
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available