N5S (p.Asn5Ser) variant of SOCS1 (O15524)
N5S (p.Asn5Ser) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
N5S (p.Asn5Ser) variant details
- p.Asn5Ser
- cosmic curated COSV59659
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.11
- CADD 18.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 7.3e-06)
- Structural context available