N11S (p.Asn11Ser) variant of SOCS1 (O15524)
N11S (p.Asn11Ser) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
N11S (p.Asn11Ser) variant details
- p.Asn11Ser
- ExAC rs772431210
- TOPMed rs772431210
- gnomAD rs772431210
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.05
- CADD 23.50
- PolyPhen-2 0.03
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 0.00024)
- Structural context available