E18Q (p.Glu18Gln) variant of SOCS1 (O15524)
E18Q (p.Glu18Gln) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
E18Q (p.Glu18Gln) variant details
- p.Glu18Gln
- cosmic curated COSV59659
- TOPMed rs1163730492
- gnomAD rs1163730492
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.09
- CADD 22.30
- PolyPhen-2 0.05
- SIFT 0.22
- Population evidence available
- Structural context available