C42F (p.Cys42Phe) variant of SOCS1 (O15524)
C42F (p.Cys42Phe) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
C42F (p.Cys42Phe) variant details
- p.Cys42Phe
- gnomAD rs1306590732
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.05
- CADD 19.30
- PolyPhen-2 0.01
- SIFT 0.21
- Population evidence available
- Structural context available