A9V (p.Ala9Val) variant of SOCS1 (O15524)
A9V (p.Ala9Val) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A9V (p.Ala9Val) variant details
- p.Ala9Val
- cosmic curated COSV59659
- Ensembl rs2141125525
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.09
- CADD 24.50
- PolyPhen-2 0.85
- SIFT 0.13
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.2e-05)
- Structural context available