A9G (p.Ala9Gly) variant of SOCS1 (O15524)
A9G (p.Ala9Gly) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A9G (p.Ala9Gly) variant details
- p.Ala9Gly
- cosmic curated COSV10524
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.11
- CADD 23.70
- PolyPhen-2 0.85
- SIFT 0.54
- Most common in the Latino/Admixed American population (allele frequency 0.00011)
- Structural context available